BackgroundAlthough most digital twin (DT) applications for health care have here emerged in precision medicine, DTs can potentially support the overall health care process.DTs (twinned systems, processes, and products) can be used to optimize flows, improve performance, improve health outcomes, and improve the experiences of patients, doctors, and

Abstract The PI3K/AKT/mTOR and RAF/MEK/ERK pathways are commonly activated by mutations and chromosomal translocation in vital targets.The PI3K/AKT/mTOR signaling pathway is dysregulated in nearly all kinds of neoplasms, with the component in this pathway alternations.RAF/MEK/ERK signaling cascades are used to conduct signaling from the cell surfac

Objective: To investigate the hepatoprotective effect of Opuntia read more dillenii seed oil (ODSO) on CCl4 provoked liver injury in rat.Methods: Animals were treated orally with ODSO at a concentration of 2 mL/kg, once daily for one week before the first intraperitoneal injection of CCl4, and thereafter the administration of the oil was continued

Abstract Gaming disorder is characterized by ICD 11 as persistent or recurrent gaming behavior manifested by impaired control over gaming, increasing priority given to gaming over other life interests and daily activities; and continuation or escalation of gaming despite the occurrence of negative consequences.IGD shares to a large extent neurobiol